Description
Product Characteristics:
Aliases: Cancer associated Sm like protein antibody, Cancer associated Sm-like antibody, Cancer-associated Sm-like antibody, CASM antibody, lsm1 antibody, LSM1 antibody antibody, LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) antibody, Lsm1 protein antibody, LSM1, U6 small nuclear RNA associated antibody, LSM1_HUMAN antibody, Small nuclear ribonuclear CaSm antibody, U6 snRNA associated Sm-like protein LSm1 antibody, U6 snRNA-associated Sm-like protein LSm1 antibody, YJL124C antibody
Target Information: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]